"No. No. Next question", Trump told a news conference in the White House, when asked if he "in any way, shape or form" ever urged Comey to end the probe.
These meetings come as the President is seething over the Justice Department's decision to appoint a special counsel.
Trump is leaving Friday for his first foreign trip, to the Mideast and beyond, which aides hope can have the effect of refocusing a White House in disarray. Republicans on Capitol Hill hoped the same, reasoning that the appointment of a special counsel could free them to work on a major tax overhaul and other matters without constant distractions.
Trump said he was about to name a replacement for Comey, another move to settle the waters.
The rumored front-runner for the position is former Democratic Sen. But several changed their mind after The New York Times reported that the President asked Mr Comey to drop an investigation into former National Security Advisor Michael Flynn, according to a memo reportedly written by Mr Comey.
Did he in fact collude with Russian Federation in his campaign to defeat Democrat Hillary Clinton? He also said "it is obvious" that some people want to harm Trump.
However another answer on that subject seemed both more specific and perhaps ambiguous.
"This is the single greatest witch hunt of a politician in American history!" added Trump.Democrats rejected Trump's characterization."This is a truth hunt", said Democratic Senator Amy Klobuchar.Russia has denied USA intelligence agencies' conclusion that it interfered in the election campaign to try to tilt the vote in Trump's favor.
Mueller, a former federal prosecutor at the Justice Department, was confirmed as FBI director days before the September 11, 2001, attacks that would ultimately shape his tenure. "It appears to me now to be considered a criminal investigation", Mr Graham told reporters after Mr Rosenstein briefed all 100 senators on the investigation.
But the lingering question hanging over the press conference was what the appointment of Mueller meant for his presidency.
Because it was a closed briefing, it's unclear exactly how Rosenstein described how he knew Trump would fire Comey. "Mr. Rosenstein has done the right thing", Senate Minority Leader Chuck Schumer of NY said Thursday on the Senate floor. The reports, based on a memo Comey wrote after their conversation, fueled allegations by Democrats that the Republican president may have been trying to obstruct the investigation.
"That was a poor, poor performance", Trump said.
Senate Intelligence Committee Chairman Richard Burr says the appointment of former FBI Director Robert Mueller as a special counsel is a "good decision" that "assures the American people that there's no undue influence" in the probe of Russian meddling in last year's election.
President Donald Trump says that the appointment of a special counsel for the ongoing investigation into his campaign's ties to Russian Federation "divides the country".
House Speaker Paul Ryan said the appointment was consistent with his goal of ensuring that "thorough and independent investigations are allowed to follow the facts wherever they may lead".
Both the Senate and the House of Representatives still have committees conducting their own probes into whether Trump campaign advisers conspired with Russian operatives to influence the 2016 United States presidential election.
On a day of fast-moving developments, the House intelligence committee announced that it, too, had asked for documents, in this case from the Federal Bureau of Investigation and the Justice Department.
The No. 2 Senate Republican, John Cornyn of Texas, said he is supportive of investigations in Congress but expressed concern about the "proliferation" of hearings.