Peter Hook, the bass player from Manchester bands Joy Division and New Order, led the crowd on the Pyramid Stage in reflecting on "our hopes and our prayers for life, love and freedom, the things we are here to celebrate".
Immediately before them, rock group Royal Blood celebrated with champagne on stage as their second album, How Did We Get So Dark, entered the charts at number one.
They wrote: "On Friday at 10.40am, there will be a minute's silence at the Pyramid to honour those affected by the recent events in Manchester & London. God bless you all".
Before the novelist, poet and MC takes to the stage, a girl races past assuring her friend that Tempest is worth barging to the front for as she "proper pumps you up".
Guitarist Ed O'Brien said they would "leave their ego at the gate" and embrace the spirit of the festival.
Together with the organiser of the music festival, Beckham launched an affordable housing project in the area by planting a tree. She said she spent Wednesday looking for shade and cold beer after arriving as soon as the gates opened.
I tapped him on the shoulder and said, "I'm off mate, see you later.' He turned around and went, 'If you do, you'll probably live the rest of your life regretting it".
Thursday's show was nearly a re-run of that show, as fans joined in with the band's new single, Can Do.
"I know that you would not have chosen to put a political opportunity at Glastonbury ahead of our nation's Armed Forces and veterans and that you must have felt very uneasy about the scheduling decisions presumably taken by your staff".