Austin Ernst and Angel Yin will both make their Solheim Cup debuts for the United Staes as captain's wild card selections at Des Moines Country Club in Iowa from August 18-20.
But Sorenstam has taken the gamble of picking rookies Madeline Sagstrom and Emily Pedersen to complete her 12-strong team for the contest in Iowa from August 18-20, with the visitors seeking just a second win on USA soil.
Georgia Hall and Florentyna Parker are two other rookies who qualified outright, but Sorenstam has no doubts about her team.
The Scottish No 1, pictured right, was still very much in the running coming into the final two counting events but finished outside the top 50 in the Scottish Open at Dundonald Links before the 2009 British Open victor missed the cut with her final throw of the dice in Fife. "We can't wait to get there in a week's time".
Sorenstam admitted she is proud to be leading Europe.
"Catriona lives and breathes the Solheim Cup but she took the decision with the maturity and professionalism we know her for", said the Swede. "She was strong and mature and I am happy she is on the team either way".
Ernst, whose only LPGA tour win came in the 2014 Portland Classic, and Yin, a powerful 18-year-old from California, were chosen by captain Juli Inkster for the defence of the trophy on Sunday at the conclusion of the Women's British Open. "As for Angel, the team loves her, so it is a win, win".
EUROPE: Carlota Ciganda, Jodi Ewart Shadoff, Georgia Hall, Charley Hull, Karine Icher, Florentyna Parker, Suzann Pettersen, Mel Reid, Anna Nordqvist (captain's pick), Caroline Masson (captain's pick), Emily Kristine Pedersen (captain's pick), Madelene Sagstrom (captain's pick).