But the showdown against Alexandra Vlajk of Hungary, at the T-Mobile Arena, was forced to be canned after the foe had an issue with her pre-fight blood test.
Adams, a double-Olympic champion has won her two fights as a pro, overcoming Virginia Noemi Carcamo and Maryan Salazar.
But the bout was abandoned just before the fighters were due in the ring.
"I'm devastated that I'm not boxing tonight, due to a problem with my opponent, thank you everyone for your support and kind messages", Adams tweeted.
Adams jumped at the late chance to appear on the high-profile card, hoping to realise an ambition she has held since the days when she would stay up into the early hours to watch her heroes on television.
The Las Vegas fight on a huge pay-per-view event would have been Adams's most high profile fight as a professional and increased her exposure in the United States and internationally.
"I don't know if we've ever had women on the undercard of such a big event before, or in Vegas".