Asked about Mkhitaryan's future in Manchester, Mourinho - speaking ahead of Monday's visit of Stoke City - said: "My approach is that every player has a price".
"The balance of the squad is made in the summer, unless you have a dramatic situation with a crazy number of injuries and you are pushed for emergency deals".
The Chilean's future has become increasingly unclear in January, with United muscling in on a player who seemed destined for the Etihad Stadium.
It is obvious that there are some fine players in this team.
"Then it's up to us to make the decision yes or no. It's up to us to make the right price".
Alexis Sanchez didn't travel with the Arsenal squad to Bournemouth and won't feature in Sunday's Premier League match, Goal has learned. Whoever takes him on next will face a rebuilding job to get the playmaker back to what he was not so long ago.
'Always looking to improve the team and we have had some good acquisitions over the years.
Manchester United have lined up three potential forwards this January - and all from Premier League clubs.
Stoke City are winless in their last 17 trips to Manchester United in all competitions (D2 L15), since a 1-0 win in April 1976.
Mourinho's side will be recharged following a week in Dubai, however, and the Red Devils should have more than enough to make it back-to-back wins in the Premier League.
Jose Mourinho admits Manchester United could decide to sell Henrikh Mkhitaryan during the January transfer window. The paper reports that the new Stamford Bridge boss could be Massimiliano Allegri, who is currently at Juventus, or former Barcelona coach Luis Enrique.
"If in the winter you do one of the three, then in the summer you do three minus one". It doesn't matter the level.
Everton are prepared to pay £20million for Arsenal's Theo Walcott, according to the Telegraph.
"If we do something now we don't need to do in the summer again". He was starting having minutes here and there, he had a start, he had 60 minutes of one game and started another one, and had 45 [minutes], and he was not happy with his feelings.
Mkhitaryan has been linked with a move back to Dortmund but his boss did offer him some hope.