Her possible run came up at a media call with President Trump.
The POTUS looked confident that he would "beat Oprah". Oprah would always be my first choice, ' he said. "I knew her very well", he added. She had Donald Trump - this is before politics - her last week. "It was the right person giving the right speech at the right time". "I don't think she has the heart of America's best interest in her mind".
LINDA MOTTRAM: Donald Trump there.
She said she likes the fact that Winfrey "reads with comprehension, is inclusive and is global".
"Where do I send my check?" she joking told DeGeneres.
The ceremony was filled with speeches addressing the sexual harassment scandals that have plagued Hollywood over the last year.
Jeremy Young, thank you for your time.
I think she's been a plausible candidate at least since 2008 when she stumped for Barack Obama in the south, in the primary and possibly even longer than that. I believe that she could make a difference in this country. "I do think she's intrigued by the idea". She is a terrific woman.
"We all know that the press is under siege at the moment", Winfrey said. So if that's true, I just want to say: Oprah, you will never be president! I mean it is so intense. ".When that new day finally dawns, it will be because of a lot of magnificent women, many of whom are right here in this room tonight, and some pretty phenomenal men".
"I disagree very much on her policy", she said. But their time is up.
Oprah is the first black woman to receive the award.
Going on he said campaigning against her would be "a lot of fun". But the deputy press secretary Hogan Gidely said, "We welcome the challenge, whether it be Oprah Winfrey or anybody else". She said she's not sure she wants to move into a smaller place.
Gayle King and Oprah Winfrey in New York on Oct. 25, 2016. Would Oprah be able to win a Democratic Party primary campaign against Sen.
Trump has expressed public admiration for Winfrey on other talk shows.
And so does William Kristol, who served in the George H W Bush White House and founded conservative magazine The Weekly Standard.